There seems to be no shortage of clubs for sports fans and pop/ dance clubs. How about a club for geeks and nerds like the characters on Big Bang Theory. There are lots of us out there, many singles, that don't like the regular club scene. This could be a golden opportunity for a creative club owner to cash-in on an untapped market .
Perhaps to start , once or twice a week have a geek theme night showing PBS NOVA, or stuff from science/sci-fi, discovery channels, on TVs instead of sports, etc.